Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-205-3p
miRNA |
Promotes proliferation, reduces apoptosis, linked to poor prognosis | Reduces survival, promotes therapy resistance | Breast Cancer |
PubMed
Reference PMID: 31578772 |
|
miR-182-3p
miRNA |
Targets TRF2, induces DNA damage leading to ... | Impaired tumor growth in triple-negative breast... | Breast Cancer |
PubMed
Reference PMID: 36426578 |
|
miR-17-5p
miRNA |
HBP1 induces apoptosis | miR-17-5p plays an important role in breast cancer cell invasion and migration by suppressing HBP1 and subsequent activation of Wnt/?-catenin. | Breast Cancer |
PubMed
Reference PMID: 20505989 |
|
miR-205-5p
miRNA |
Modulates Hippo signaling pathway to trigger apoptosis | Regulates tumor suppression pathways effectively | Breast Cancer |
PubMed
Reference PMID: 37311160 |
|
miR-125a-5p
miRNA |
inhibits proliferation and induces apoptosis | miR?125a?5p reverses EMT and restores drug sensitivity by negatively regulating TAFAZZIN in breast cancer | Breast Cancer |
PubMed
Reference PMID: 34549308 |
|
hsa-miR-125b-5p
miRNA |
Targets KIAA1522 (oncogenic protein) | Tumor suppressor; inhibits proliferation and metastasis | Breast Cancer |
PubMed
Reference PMID: 30177391 |
|
hsa-miR-1297
miRNA |
Targets FA2H (fatty acid 2-hydroxylase) | Oncogene; promotes proliferation, EMT and survival (knockdown increases apoptosis) | Breast Cancer |
PubMed
Reference PMID: 33014155 |
|
hsa-miR-130a-3p
miRNA |
Targets SATB1 (regulating chromatin/EMT) | Tumor suppressor; suppresses proliferation and promotes apoptosis (H19 knockdown increases miR-130a-3p) | Breast Cancer |
PubMed
Reference PMID: 33324070 |
|
hsa-miR-130a-5p
miRNA |
Predicted targets include PTEN/JAK-STAT pathway; downregulated in BC | Tumor suppressor; downregulation observed in BC suggests it normally inhibits growth | Breast Cancer |
PubMed
Reference PMID: 32972352 |
|
hsa-miR-130b-3p
miRNA |
overexpression often inhibits apoptosis | ESR1/miR-130b-3p/HOTAIR may be promising targets for clinical treatment of endocrine therapy-resistant breast cancer | Breast Cancer |
PubMed
Reference PMID: 30142342 |