Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-182-3p
miRNA |
Targets TRF2, induces DNA damage leading to strong apoptosis activation | Impaired tumor growth in triple-negative breast cancer | Breast Cancer |
PubMed
Reference PMID: 36426578 |
|
miR-20a-5p
miRNA |
High expression of miR-20a-5p significantly decreased both the mRNA and protein levels of RUNX3 | overexpression of miR-20a-5p promoted the migration and invasion of TNBC cells in vitro | Breast Cancer |
PubMed
Reference PMID: 29864933 |
|
miR-361-3p
miRNA |
Inhibition increases apoptosis and reduces proliferation in resistant BC cells | Potential new treatment for advanced breast cancer | Breast Cancer |
PubMed
Reference PMID: 36622663 |
|
miR-138-5p
miRNA |
Induces apoptosis by upregulating Caspase-9 and Caspase-3, arrests cell cycle at sub-G1 phase | Anti-proliferative effects and motility reduction | Breast Cancer |
PubMed
Reference PMID: 33545160 |
|
miR-145-5p
miRNA |
Regulates KLF5 expression, promoting apoptosis in breast cancer cells | Promotes apoptosis and reduces proliferation | Breast Cancer |
PubMed
Reference PMID: 37997376 |
|
miR-21
miRNA |
Oncogenic miRNA suppressing pro-apoptotic genes and promoting cell survival | Promotes breast cancer cell survival and metastasis | Breast Cancer |
PubMed
Reference PMID: 39226804 |
|
miR-106a
miRNA |
Decreases apoptosis and increases breast cancer cell chemoresistance | Enhanced proliferation and chemoresistance | Breast Cancer |
PubMed
Reference PMID: 30570350 |
|
miR-155
miRNA |
Regulates apoptotic pathways, implicated in tumorigenesis | Role in breast cancer progression and resistance | Breast Cancer |
PubMed
Reference PMID: 26898434 |
|
miR-200c
miRNA |
Overexpression of miR?200c inhibited MDA?MB?231 cell proliferation and resulted in the induction of apoptosis | miR?200c may function as a tumor suppressor gene in TNBC | Breast Cancer |
PubMed
Reference PMID: 24821285 |
|
miR-17-5p
miRNA |
Acts as an oncogene, inhibits apoptosis through targeting PTEN | Contributes to poor prognosis and resistance | Breast Cancer |
PubMed
Reference PMID: 26199650 |