Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-106a
miRNA |
Upregulates BCL2, promotes proliferation, inhibits apoptosis | Linked to tumor growth and therapeutic resistance | Breast Cancer |
PubMed
Reference PMID: 32021439 |
|
miR-125b
miRNA |
Downregulates MCL-1, synergistic with doxorubicin for apoptosis | Promotes apoptosis, linked to improved outcomes | Breast Cancer |
PubMed
Reference PMID: 25894378 |
|
miR-134
miRNA |
Increases drug sensitivity in triple-negative BC by regulating STAT5B | Increases therapy sensitivity, suppresses metastasis | Breast Cancer |
PubMed
Reference PMID: 26416415 |
|
miR-139-5p
miRNA |
Inhibits COL11A1 to promote apoptosis and inhibit BC proliferation | Promotes apoptosis, inhibits BC growth | Breast Cancer |
PubMed
Reference PMID: 32233587 |
|
miR-143-3p
miRNA |
Targets MYBL2, inhibits proliferation, induces apoptosis | Inhibits growth, enhances treatment efficacy | Breast Cancer |
PubMed
Reference PMID: 29268817 |
|
miR-148a
miRNA |
Downregulates ALCAM, reduces tamoxifen resistance in ER+ BC | Improves therapy response in tamoxifen-resistant cases | Breast Cancer |
PubMed
Reference PMID: 28063929 |
|
miR-152
miRNA |
Modulates KIF4A/ZEB1 axis, suppressing apoptosis and invasion | Suppresses invasion and promotes therapy sensitivity | Breast Cancer |
PubMed
Reference PMID: 28063929 |
|
miR-193b
miRNA |
Regulates MCL-1, enhances doxorubicin sensitivity | Enhances apoptosis, linked to reduced metastasis | Breast Cancer |
PubMed
Reference PMID: 26526790 |
|
miR-199a-3p
miRNA |
Downregulates TFAM, enhancing sensitivity to cisplatin | Improves treatment sensitivity, reduces cell viability | Breast Cancer |
PubMed
Reference PMID: 28126676 |
|
miR-200b
miRNA |
Induces apoptosis by targeting Sp1, inhibiting BC proliferation | Induces apoptosis, suppresses tumor growth | Breast Cancer |
PubMed
Reference PMID: 25639535 |