Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-205-5p
miRNA |
Modulates Hippo signaling pathway to trigger apoptosis | Regulates tumor suppression pathways effectively | Breast Cancer |
PubMed
Reference PMID: 37311160 |
|
miR-7-5p
miRNA |
Targets REGg to suppress proliferation and induce apoptosis in BC cells | Induces apoptosis and suppresses proliferation in triple-negative BC | Breast Cancer |
PubMed
Reference PMID: 25511742 |
|
miR-15a
miRNA |
Suppresses BMI1, downregulates BCL2, upregulates pro-apoptotic proteins | Promotes mitochondrial apoptosis and reduces proliferation | Breast Cancer |
PubMed
Reference PMID: 28655885 |
|
miR-16
miRNA |
Enhances mitochondrial apoptosis pathway via reactive oxygen species | Increases sensitivity to therapies and survival rates | Breast Cancer |
PubMed
Reference PMID: 27596816 |
|
miR-17-5p
miRNA |
Inhibits STAT3 to upregulate p53, promoting apoptosis in BC cells | Improves therapeutic response and reduces metastasis | Breast Cancer |
PubMed
Reference PMID: 28178652 |
|
miR-23a
miRNA |
Promotes survival and migration, modulating XIAP-mediated autophagy | Facilitates drug resistance and cell survival | Breast Cancer |
PubMed
Reference PMID: 29050223 |
|
miR-27a
miRNA |
Regulates apoptosis sensitivity via BAK-SMAC/DIABLO-XIAP axis | Enhances cell proliferation and tumor resistance | Breast Cancer |
PubMed
Reference PMID: 30365154 |
|
miR-32
miRNA |
Targets FBXW7, promotes proliferation, suppresses apoptosis | Reduces apoptosis, linked to poor prognosis | Breast Cancer |
PubMed
Reference PMID: 28149200 |
|
miR-34a
miRNA |
Regulates circGFRA1, increases GFRA1 expression, enhances apoptosis | Promotes apoptosis and reduces tumor growth | Breast Cancer |
PubMed
Reference PMID: 29037220 |
|
miR-100
miRNA |
Regulates MTMR3, promotes apoptosis in BC cells | Suppresses proliferation, induces apoptosis | Breast Cancer |
PubMed
Reference PMID: 26130569 |