Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-3653
miRNA |
Blocks autophagy via ATG12 and AMBRA1 | Inhibits EMT and metastasis | Breast Cancer |
PubMed
Reference PMID: 37464439 |
|
miR-25
miRNA |
Upregulate ULK1 | Induce autophagy | Breast Cancer |
PubMed
Reference PMID: 25026296 |
|
miR-200c
miRNA |
Reduces expression levels of LC3 and UBQLN1 | Breast Cancer |
PubMed
Reference PMID: 25044403 |
|
|
miR-27a
miRNA |
miR-27a suppressed LC3-II and p62 expressions to inhibit autophagy | and sensitized cancer cells to doxorubicin and paclitaxel | Breast Cancer |
PubMed
Reference PMID: 32066826 |
|
miR-129-5p
miRNA |
miR-129-5p suppressed HMGB1 to inhibit autophagy | sensitized breast cancer cells to taxol treatment | Breast Cancer |
PubMed
Reference PMID: 31664305 |
|
miR-489
miRNA |
miR-489 downregulated ULK1 to block autophagy | sensitized breast cancer cells to doxorubicin treatment | Breast Cancer |
PubMed
Reference PMID: 29784669 |
|
miR-23b-3p
miRNA |
miR-23b-3p downregulated SLC6A14 to promote autophagy | tamoxifen resistance | Breast Cancer |
PubMed
Reference PMID: 31269432 |
|
miR-21
miRNA |
miR-21 could promote PI3K/AKT/mTOR pathway to inhibit autophagy | promote resistance towards both tamoxifen and fulvestrant | Breast Cancer |
PubMed
Reference PMID: 26796263 |
|
miR-101
miRNA |
miR-101 suppressed ATG4D, STMN1 and RAB5A expressions to block autophagy | promote tamoxifen-induced cells death | Breast Cancer |
PubMed
Reference PMID: 21915098 |
|
miR-125b-5p
miRNA |
miR-125b-5p suppressed PAD2 expression to promote both autophagy and apoptosis. | sensitized cancer cells to both tamoxifen and docetaxel | Breast Cancer |
PubMed
Reference PMID: 31601253 |