Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-30a-5p
miRNA |
Not reported | Tumor suppressor: inhibits BC cell proliferation (targets UBE3C, CyclinB1/D1, c-Myc) | Breast Cancer |
PubMed
Reference PMID: 22476851 |
|
miR-30b-5p
miRNA |
Not reported | Oncogenic (especially in TNBC): promotes proliferation, migration, invasion by targeting ASPP2 and activating AKT | Breast Cancer |
PubMed
Reference PMID: 32420372 |
|
miR-31-5p
miRNA |
Not reported | Tumor suppressor (anti-metastatic): restoration of miR-31-5p inhibits TNBC cell migration and invasion | Breast Cancer |
PubMed
Reference PMID: 29796229 |
|
miR-33a-5p
miRNA |
Not reported | Tumor suppressor in TNBC: inhibits proliferation and metastasis by targeting EZH2 | Breast Cancer |
PubMed
Reference PMID: 32206036 |
|
miR-374b-5p
miRNA |
Not reported | Tumor suppressor in TNBC: higher miR-374b-5p levels predict better survival; restoration suppresses cell invasion and proliferation | Breast Cancer |
PubMed
Reference PMID: 26062749 |
|
miR-374c-5p
miRNA |
Not reported | Tumor suppressor: downregulated in BC; overexpression inhibits proliferation, migration and EMT, and induces apoptosis (via TAF7/DEPDC1) | Breast Cancer |
PubMed
Reference PMID: 31162714 |
|
miR-16-5p
miRNA |
Enhances autophagy through ZBTB16/G6PD axis | Increases antitumor efficacy in HER2-positive BC | Breast Cancer |
PubMed
Reference PMID: 38110365 |
|
circCDYL
miRNA |
Promotes autophagy via miR-1275-ATG7/ULK1 axis | Enhances breast cancer progression | Breast Cancer |
PubMed
Reference PMID: 32213200 |
|
circEGFR
miRNA |
Facilitates autophagy through miR-224-5p/ATG13/ULK1 loop | Promotes TNBC progression and metastasis | Breast Cancer |
PubMed
Reference PMID: 38280941 |
|
miR-224-5p
miRNA |
Inhibits autophagy by targeting Smad4 | Facilitates metastasis | Breast Cancer |
PubMed
Reference PMID: 30389135 |