Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
MEG3
lncRNA |
Activates NLRP3/caspase-1/GSDMD pathway to induce pyroptosis | Anti-tumor effect in triple-negative breast cancer (TNBC) by inducing pyroptosis | Breast Cancer |
PubMed
Reference PMID: 34326697 |
|
Malat1
lncRNA |
Suppresses pyroptosis and T cell-mediated killing by inducing SERPINB6B | Promotes tumor initiation, metastasis, and immune evasion | Breast Cancer |
PubMed
Reference PMID: 38195932 |
|
8 pyroptosis-related lncRNAs 0.0, AC004585.1, DLGAP1-AS1, TNFRSF14-AS1, AL606834.2, Z68871.1, AC009119.1, LINC01871, AL136368.1
lncRNA |
Risk model assessing immune infiltration and tumor microenvironment interactions | Prognostic and therapeutic potential in breast cancer | Breast Cancer |
PubMed
Reference PMID: 35702100 |
|
RP11-459E5.1, RP11-1070N10.3, RP11-817J15.3
lncRNA |
Identified via risk model correlating with immune checkpoints and mutation burden | High correlation with survival outcomes | Breast Cancer |
PubMed
Reference PMID: 35360412 |
|
8 differentially expressed lncRNAs (AL928768.3,CTA.384D8.35,CTB.33O18.1,CTB.33O18.2,LINC00519,LINC00987,PTPRD.AS1,RP11.1070N10.3, RP5.1028K7.2
lncRNA |
Linked to pyroptosis and breast cancer lung metastasis | Correlates with survival, immune responses, and PD-1 therapy response | Breast Cancer |
PubMed
Reference PMID: 35309942 |
|
9-pyroptosis-associated lncRNAs AL928768.3, CTA.384D8.35, CTB.33O18.1, CTB.33O18.2, LINC00519, LINC00987, PTPRD.AS1, RP11.1070N10.3, RP5.1028K7.2
lncRNA |
Associated with immune microenvironment and prognosis | High predictive power for survival and therapeutic response | Breast Cancer |
PubMed
Reference PMID: 34616734 |
|
8 differentially expressed lncRNAs 0.0, AC004585.1, DLGAP1-AS1, TNFRSF14-AS1, AL606834.2, Z68871.1, AC009119.1, LINC01871, AL136368.1
lncRNA |
Integrated risk model with immune infiltration and signaling analysis | Prognostic significance and therapeutic implications | Breast Cancer |
PubMed
Reference PMID: 34632690 |
|
7 pyroptosis-related lncRNAs AC005034.5, AC027307.2,AC121761.2,AL451085.2, AL513477.2,LINC01871,U73166.1
lncRNA |
Risk model linked to angiogenesis, TGF-β, and immune cell infiltration | Potential biomarkers and therapeutic targets | Breast Cancer |
PubMed
Reference PMID: 34552353 |