Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
circ-DNMT1
circRNA |
Regulating the oncogenic proteins P53 and AUF1 in breast cancer cells. | Enhance the autophagy of breast cancer cells and promote breast cancer progression | Breast Cancer |
PubMed
Reference PMID: 29973691 |
|
circ0006528
circRNA |
Promotes the expression of LC3-II | Induce autophagy in breast cancer cells | Breast Cancer |
PubMed
Reference PMID: 33061434 |
|
circABCB10
circRNA |
circABCB10 adsorbs LET7A-5p to function as ceRNA, thereby promoting the expression of DUSP7 | Promote autophagy in breast cancer cells and paclitaxel drug resistance | Breast Cancer |
PubMed
Reference PMID: 32273769 |
|
hsa_circ_0092276
circRNA |
Altering autophagy-related gene 7 (ATG7) via sponging miR-384 | Contribute to doxorubicin-resistance in Breast cancer cells | Breast Cancer |
PubMed
Reference PMID: 34023560 |
|
circSEPT9
circRNA |
circSEPT9 sponge miR-637 | mechanism involved remains unclear. | Breast Cancer |
PubMed
Reference PMID: 32264877 |
|
H19
lncRNA |
Promotes protective autophagy by inhibiting SAHH, causing SAH accumulation that prevents DNMT3B-mediated methylation of the BECN1 promoter, upregulating Beclin1 and activating autophagy. | Drives tamoxifen resistance in ER+ breast cancer via increased autophagy. | Breast Cancer |
PubMed
Reference PMID: 31340867 |
|
hsa-miR-221-3p
miRNA |
Targets p27^Kip1; associated with autophagic cell death signaling in MCF-7 context (reviews). | Confers tamoxifen resistance in ER+ breast cancer via p27^Kip1 downregulation; autophagy implicated. | Breast Cancer |
PubMed
Reference PMID: 18708351 |
|
hsa-miR-222-3p
miRNA |
Targets p27^Kip1; linked with autophagy modulation in MCF-7 per reviews. | Confers tamoxifen resistance in ER+ breast cancer via p27^Kip1 downregulation; autophagy implicated. | Breast Cancer |
PubMed
Reference PMID: 18708351 |
|
hsa-miR-200c-3p
miRNA |
Inhibits irradiation?induced autophagy by targeting UBQLN1; enhances radiosensitivity. | In MDA?MB?231/BT549 (TNBC) cells, miR?200c overexpression reduces autophagy and increases radiosensitivity. | Breast Cancer |
PubMed
Reference PMID: 25044403 |
|
hsa-miR-129-5p
miRNA |
Attenuates irradiation?induced autophagy by directly targeting HMGB1; increases radiosensitivity. | In MDA?MB?231 (TNBC) cells, overexpression inhibits autophagy and sensitizes to radiation. | Breast Cancer |
PubMed
Reference PMID: 26720492 |