Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
OTUD6B-AS1
lncRNA |
miR-26a-5p/MTDH pathway | Promotes paclitaxel resistance | Breast Cancer |
PubMed
Reference PMID: 34740994 |
|
SNHG3
lncRNA |
c-Myc/SNHG3/mTOR axis | Promotes autophagy and inhibits migration | Breast Cancer |
PubMed
Reference PMID: 36963166 |
|
PRKCQ-AS1
lncRNA |
miR-361-5p/PIK3C3 mediated | Regulates paclitaxel resistance | Breast Cancer |
PubMed
Reference PMID: 36732923 |
|
GAS5
lncRNA |
overexpression of GAS5 led to an increase in ULK1/2 protein levels | By promoting the activation of ULK1/2 and initiating autophagy | Breast Cancer |
PubMed
Reference PMID: 32705220 |
|
HOTAIR
lncRNA |
HOTAIR can act as a sponge for miRNA-34a | HOTAIR promotes the invasion of breast cancer cells through β-catenin and MMPs | Breast Cancer |
PubMed
Reference PMID: 29469819 |
|
H19
lncRNA |
Induces autophagy activation via the H19/SAHH/DNMT3B axis, | Promotes tamoxifen resistance in breast cancer via autophagy | Breast Cancer |
PubMed
Reference PMID: 31340867 |
|
EGOT
lncRNA |
Upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions | EGOT enhances autophagy, sensitizes cancer cells to paclitaxel | Breast Cancer |
PubMed
Reference PMID: 30999914 |
|
UCA1
lncRNA |
UCA1 functions as a competing endogenous RNA (ceRNA), | UCA1 drives trastuzumab resistance and sustains breast cancer cell viability via the autophagy pathway. | Breast Cancer |
PubMed
Reference PMID: 29408336 |
|
ZNF649-AS1
lncRNA |
Promotes the transcriptional activity of the ATG5 gene | By promoting autophagy, ZNF649-AS1 contributes to trastuzumab resistance | Breast Cancer |
PubMed
Reference PMID: 32735773 |
|
OTUD6B
lncRNA |
OTUD6B-AS1 acts as a competing endogenous RNA (ceRNA), binding to miR-26a-5p and sequestering it. | OTUD6B-AS1 supports cancer cell survival by promoting autophagy | Breast Cancer |
PubMed
Reference PMID: 34740994 |