Explore this research category across breast cancer datasets
| RNA Name | Mechanism of Action | Effect on Cancer | Cancer Type | Reference |
|---|---|---|---|---|
|
miR-489
miRNA |
miR-489 downregulated ULK1 to block autophagy | sensitized breast cancer cells to doxorubicin treatment | Breast Cancer |
PubMed
Reference PMID: 29784669 |
|
miR-23b-3p
miRNA |
miR-23b-3p downregulated SLC6A14 to promote autophagy | tamoxifen resistance | Breast Cancer |
PubMed
Reference PMID: 31269432 |
|
miR-21
miRNA |
miR-21 could promote PI3K/AKT/mTOR pathway to inhibit autophagy | promote resistance towards both tamoxifen and fulvestrant | Breast Cancer |
PubMed
Reference PMID: 26796263 |
|
miR-101
miRNA |
miR-101 suppressed ATG4D, STMN1 and RAB5A expressions to block autophagy | promote tamoxifen-induced cells death | Breast Cancer |
PubMed
Reference PMID: 21915098 |
|
miR-125b-5p
miRNA |
miR-125b-5p suppressed PAD2 expression to promote both autophagy and apoptosis. | sensitized cancer cells to both tamoxifen and docetaxel | Breast Cancer |
PubMed
Reference PMID: 31601253 |
|
miR-26b
miRNA |
miR-26b downregulated DRAM1 expression to inhibit autophagy | sensitize breast cancer cells to irradiation | Breast Cancer |
PubMed
Reference PMID: 29399189 |
|
miR-200c
miRNA |
miR-200 downregulated UBQLN1 to block autophagy | sensitized breast cancer cells to irradiation | Breast Cancer |
PubMed
Reference PMID: 25044403 |
|
miR-20a
miRNA |
Targets RB1CC1/FIP200, negatively regulates autophagy | Attenuates basal and rapamycin-induced autophagy | Breast Cancer |
PubMed
Reference PMID: 26829385 |
|
miR-20b
miRNA |
Targets RB1CC1/FIP200, negatively regulates autophagy | Attenuates basal and rapamycin-induced autophagy | Breast Cancer |
PubMed
Reference PMID: 26829385 |
|
miR-195
miRNA |
Targets mitofusin-2, upregulates autophagy | Enhances mitochondrial SOD-2 expression, promotes apoptosis | Breast Cancer |
PubMed
Reference PMID: 30932749 |