Apoptosis RNA Database

RNA Name	Mechanism of Action	Effect on Cancer	Cancer Type	Reference
miR-155 miRNA	Regulates apoptotic pathways, implicated in tumorigenesis	Role in breast cancer progression and resistance	Breast Cancer	PubMed Reference PMID: 26898434
miR-200c miRNA	Overexpression of miR?200c inhibited MDA?MB?231 cell proliferation and resulted in the induction of apoptosis	miR?200c may function as a tumor suppressor gene in TNBC	Breast Cancer	PubMed Reference PMID: 24821285
miR-17-5p miRNA	Acts as an oncogene, inhibits apoptosis through targeting PTEN	Contributes to poor prognosis and resistance	Breast Cancer	PubMed Reference PMID: 26199650
miR-205-5p miRNA	Modulates Hippo signaling pathway to trigger apoptosis	Regulates tumor suppression pathways effectively	Breast Cancer	PubMed Reference PMID: 37311160
miR-7-5p miRNA	Targets REGg to suppress proliferation and induce apoptosis in BC cells	Induces apoptosis and suppresses proliferation in triple-negative BC	Breast Cancer	PubMed Reference PMID: 25511742
miR-15a miRNA	Suppresses BMI1, downregulates BCL2, upregulates pro-apoptotic proteins	Promotes mitochondrial apoptosis and reduces proliferation	Breast Cancer	PubMed Reference PMID: 28655885
miR-16 miRNA	Enhances mitochondrial apoptosis pathway via reactive oxygen species	Increases sensitivity to therapies and survival rates	Breast Cancer	PubMed Reference PMID: 27596816
miR-17-5p miRNA	Inhibits STAT3 to upregulate p53, promoting apoptosis in BC cells	Improves therapeutic response and reduces metastasis	Breast Cancer	PubMed Reference PMID: 28178652
miR-23a miRNA	Promotes survival and migration, modulating XIAP-mediated autophagy	Facilitates drug resistance and cell survival	Breast Cancer	PubMed Reference PMID: 29050223
miR-27a miRNA	Regulates apoptosis sensitivity via BAK-SMAC/DIABLO-XIAP axis	Enhances cell proliferation and tumor resistance	Breast Cancer	PubMed Reference PMID: 30365154

Apoptosis RNA Database

122 research entries found