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Apoptosis RNA Database
Explore this research category across breast cancer datasets
122
TOTAL APOPTOSISENTRIES
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122 research entries found
APOPTOSIS
RNA Name
Mechanism of Action
Effect on Cancer
Cancer Type
Reference
BCL2L1
mRNA
BCL2L1 (BCL-xL) is an anti-apoptotic Bcl-2 family protein that sequesters pro-apoptotic BH3-only proteins and Bax/Bak to prevent MOMP and apoptosis.
Overexpression in TNBC contributes to chemoresistance; BCL-xL inhibition enhances apoptosis and chemosensitivity.
Breast Cancer
PubMed
Reference
PMID: 38898061
CASP10
mRNA
Initiator caspase in extrinsic apoptosis (death receptor pathway).
Expression observed in TNBC; functional studies limited in last 10 years but expression associated with apoptosis responses.
Breast Cancer
PubMed
Reference
PMID: 40806590
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