Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities
| RNA Name | Mechanism of Action | Effect on Cancer | Reference |
|---|---|---|---|
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miR-145-5p
miRNA |
Regulates KLF5 expression, promoting apoptosis in breast cancer cells | Promotes apoptosis and reduces proliferation | PMID: 37997376 |
External Database SearchDetailed Information
RNA Name:
miR-145-5p
Mechanism of Action:
Regulates KLF5 expression, promoting apoptosis in breast cancer cells
Effect on Cancer:
Promotes apoptosis and reduces proliferation
PMID:
37997376
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miR-21
miRNA |
Oncogenic miRNA suppressing pro-apoptotic genes and promoting cell survival | Promotes breast cancer cell survival and metastasis | PMID: 39226804 |
External Database SearchDetailed Information
RNA Name:
miR-21
Mechanism of Action:
Oncogenic miRNA suppressing pro-apoptotic genes and promoting cell survival
Effect on Cancer:
Promotes breast cancer cell survival and metastasis
PMID:
39226804
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miR-106a
miRNA |
Decreases apoptosis and increases breast cancer cell chemoresistance | Enhanced proliferation and chemoresistance | PMID: 30570350 |
External Database SearchDetailed Information
RNA Name:
miR-106a
Mechanism of Action:
Decreases apoptosis and increases breast cancer cell chemoresistance
Effect on Cancer:
Enhanced proliferation and chemoresistance
PMID:
30570350
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miR-155
miRNA |
Regulates apoptotic pathways, implicated in tumorigenesis | Role in breast cancer progression and resistance | PMID: 26898434 |
External Database SearchDetailed Information
RNA Name:
miR-155
Mechanism of Action:
Regulates apoptotic pathways, implicated in tumorigenesis
Effect on Cancer:
Role in breast cancer progression and resistance
PMID:
26898434
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|
miR-200c
miRNA |
Overexpression of miR?200c inhibited MDA?MB?231 cell proliferation and resulted in the induction of apoptosis | miR?200c may function as a tumor suppressor gene in TNBC | PMID: 24821285 |
External Database SearchDetailed Information
RNA Name:
miR-200c
Mechanism of Action:
Overexpression of miR?200c inhibited MDA?MB?231 cell proliferation and resulted in the induction of apoptosis
Effect on Cancer:
miR?200c may function as a tumor suppressor gene in TNBC
PMID:
24821285
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|
miR-17-5p
miRNA |
Acts as an oncogene, inhibits apoptosis through targeting PTEN | Contributes to poor prognosis and resistance | PMID: 26199650 |
External Database SearchDetailed Information
RNA Name:
miR-17-5p
Mechanism of Action:
Acts as an oncogene, inhibits apoptosis through targeting PTEN
Effect on Cancer:
Contributes to poor prognosis and resistance
PMID:
26199650
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miR-205-5p
miRNA |
Modulates Hippo signaling pathway to trigger apoptosis | Regulates tumor suppression pathways effectively | PMID: 37311160 |
External Database SearchDetailed Information
RNA Name:
miR-205-5p
Mechanism of Action:
Modulates Hippo signaling pathway to trigger apoptosis
Effect on Cancer:
Regulates tumor suppression pathways effectively
PMID:
37311160
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miR-7-5p
miRNA |
Targets REGg to suppress proliferation and induce apoptosis in BC cells | Induces apoptosis and suppresses proliferation in triple-negative BC | PMID: 25511742 |
External Database SearchDetailed Information
RNA Name:
miR-7-5p
Mechanism of Action:
Targets REGg to suppress proliferation and induce apoptosis in BC cells
Effect on Cancer:
Induces apoptosis and suppresses proliferation in triple-negative BC
PMID:
25511742
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|
miR-15a
miRNA |
Suppresses BMI1, downregulates BCL2, upregulates pro-apoptotic proteins | Promotes mitochondrial apoptosis and reduces proliferation | PMID: 28655885 |
External Database SearchDetailed Information
RNA Name:
miR-15a
Mechanism of Action:
Suppresses BMI1, downregulates BCL2, upregulates pro-apoptotic proteins
Effect on Cancer:
Promotes mitochondrial apoptosis and reduces proliferation
PMID:
28655885
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miR-16
miRNA |
Enhances mitochondrial apoptosis pathway via reactive oxygen species | Increases sensitivity to therapies and survival rates | PMID: 27596816 |
External Database SearchDetailed Information
RNA Name:
miR-16
Mechanism of Action:
Enhances mitochondrial apoptosis pathway via reactive oxygen species
Effect on Cancer:
Increases sensitivity to therapies and survival rates
PMID:
27596816
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