Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities
| RNA Name | Mechanism of Action | Effect on Cancer | Reference |
|---|---|---|---|
|
KCNQ1OT1
lncRNA |
ceRNA axis KCNQ1OT1/miR-145/CCNE2 controls cell cycle and apoptosis; overexpression lowers apoptosis. | Oncogenic; reduces apoptosis; promotes growth in vitro/in vivo. | PMID: 30157476 |
External Database SearchDetailed Information
RNA Name:
KCNQ1OT1
Mechanism of Action:
ceRNA axis KCNQ1OT1/miR-145/CCNE2 controls cell cycle and apoptosis; overexpression lowers apoptosis.
Effect on Cancer:
Oncogenic; reduces apoptosis; promotes growth in vitro/in vivo.
PMID:
30157476
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SNHG8
lncRNA |
Not reported | Promoted TNBC | PMID: 34362407 |
External Database SearchDetailed Information
RNA Name:
SNHG8
Mechanism of Action:
Not reported
Effect on Cancer:
Promoted TNBC
PMID:
34362407
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SNHG1
lncRNA |
Not reported | Promoted BC In-vivo | PMID: 35027847 |
External Database SearchDetailed Information
RNA Name:
SNHG1
Mechanism of Action:
Not reported
Effect on Cancer:
Promoted BC In-vivo
PMID:
35027847
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LINC00963
lncRNA |
UBE3C overexpression inhibits apoptosis | Oncogenic; inhibits apoptosis. | PMID: 37173692 |
External Database SearchDetailed Information
RNA Name:
LINC00963
Mechanism of Action:
UBE3C overexpression inhibits apoptosis
Effect on Cancer:
Oncogenic; inhibits apoptosis.
PMID:
37173692
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MAGI2-AS3
lncRNA |
MAGI2-AS3 expression promotes apoptosis | Tumor-suppressive; promotes apoptosis. | PMID: 29679339 |
External Database SearchDetailed Information
RNA Name:
MAGI2-AS3
Mechanism of Action:
MAGI2-AS3 expression promotes apoptosis
Effect on Cancer:
Tumor-suppressive; promotes apoptosis.
PMID:
29679339
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SLC16A1-AS1
lncRNA |
miR-552-5p/WIF1 that suppresses apoptosis; knockdown triggers apoptosis. | Oncogenic; reduces apoptosis. | PMID: 35372039 |
External Database SearchDetailed Information
RNA Name:
SLC16A1-AS1
Mechanism of Action:
miR-552-5p/WIF1 that suppresses apoptosis; knockdown triggers apoptosis.
Effect on Cancer:
Oncogenic; reduces apoptosis.
PMID:
35372039
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miR-182-3p
miRNA |
Targets TRF2, induces DNA damage leading to strong apoptosis activation | Impaired tumor growth in triple-negative breast cancer | PMID: 36426578 |
External Database SearchDetailed Information
RNA Name:
miR-182-3p
Mechanism of Action:
Targets TRF2, induces DNA damage leading to strong apoptosis activation
Effect on Cancer:
Impaired tumor growth in triple-negative breast cancer
PMID:
36426578
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miR-20a-5p
miRNA |
High expression of miR-20a-5p significantly decreased both the mRNA and protein levels of RUNX3 | overexpression of miR-20a-5p promoted the migration and invasion of TNBC cells in vitro | PMID: 29864933 |
External Database SearchDetailed Information
RNA Name:
miR-20a-5p
Mechanism of Action:
High expression of miR-20a-5p significantly decreased both the mRNA and protein levels of RUNX3
Effect on Cancer:
overexpression of miR-20a-5p promoted the migration and invasion of TNBC cells in vitro
PMID:
29864933
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miR-361-3p
miRNA |
Inhibition increases apoptosis and reduces proliferation in resistant BC cells | Potential new treatment for advanced breast cancer | PMID: 36622663 |
External Database SearchDetailed Information
RNA Name:
miR-361-3p
Mechanism of Action:
Inhibition increases apoptosis and reduces proliferation in resistant BC cells
Effect on Cancer:
Potential new treatment for advanced breast cancer
PMID:
36622663
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miR-138-5p
miRNA |
Induces apoptosis by upregulating Caspase-9 and Caspase-3, arrests cell cycle at sub-G1 phase | Anti-proliferative effects and motility reduction | PMID: 33545160 |
External Database SearchDetailed Information
RNA Name:
miR-138-5p
Mechanism of Action:
Induces apoptosis by upregulating Caspase-9 and Caspase-3, arrests cell cycle at sub-G1 phase
Effect on Cancer:
Anti-proliferative effects and motility reduction
PMID:
33545160
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