Cell Death Database

Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities

388 research entries found

RNA Name	Mechanism of Action	Effect on Cancer	Reference
miR-215-5p miRNA	Part of the PRNP/miRNA hsa-miR-192-5p and hsa-miR-215-5p/lncRNA CARMN ceRNA network	Implicated in cuproptosis regulation	PMID: 36980514
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Cuproptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-215-5p Mechanism of Action: Part of the PRNP/miRNA hsa-miR-192-5p and hsa-miR-215-5p/lncRNA CARMN ceRNA network Effect on Cancer: Implicated in cuproptosis regulation PMID: 36980514
miR-92b-3p miRNA	Regulates MTF1 in the XIST/miR-92b-3p/MTF1 axis	Poor prognosis with low MTF1 expression	PMID: 36312586
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Cuproptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-92b-3p Mechanism of Action: Regulates MTF1 in the XIST/miR-92b-3p/MTF1 axis Effect on Cancer: Poor prognosis with low MTF1 expression PMID: 36312586
miR-335 miRNA	Triggers oxidative stress-mediated pyroptosis by targeting ZNF-148/SOD2 signaling cascade	Suppresses breast cancer progression	PMID: 37909239
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-335 Mechanism of Action: Triggers oxidative stress-mediated pyroptosis by targeting ZNF-148/SOD2 signaling cascade Effect on Cancer: Suppresses breast cancer progression PMID: 37909239
miR-200b miRNA	Regulates pyroptosis via JAZF1/NF-κB axis	Inhibits tumorigenesis of breast cancer	PMID: 33728753
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-200b Mechanism of Action: Regulates pyroptosis via JAZF1/NF-κB axis Effect on Cancer: Inhibits tumorigenesis of breast cancer PMID: 33728753
miR-1290 miRNA	Modulates NLRP3-mediated pyroptosis	Increases radioresistance in triple-negative breast cancer	PMID: 35471684
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-1290 Mechanism of Action: Modulates NLRP3-mediated pyroptosis Effect on Cancer: Increases radioresistance in triple-negative breast cancer PMID: 35471684
miR-182 miRNA	Inhibits NLRP3 to suppress pyroptosis	Enhances chemoresistance of breast cancer	PMID: 36905318
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-182 Mechanism of Action: Inhibits NLRP3 to suppress pyroptosis Effect on Cancer: Enhances chemoresistance of breast cancer PMID: 36905318
miR-155-5p miRNA	Promotes pyroptosis via upregulation of GSDME-N and cleaved caspase-1	Enhances anti-tumor effect of cetuximab in triple-negative breast cancer	PMID: 33472170
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: miR-155-5p Mechanism of Action: Promotes pyroptosis via upregulation of GSDME-N and cleaved caspase-1 Effect on Cancer: Enhances anti-tumor effect of cetuximab in triple-negative breast cancer PMID: 33472170
hsa-miR-573 miRNA	Mediates high expression of GSDMC, linked to pyroptosis	Associated with worse prognosis and immune infiltration in breast cancer	PMID: 36042287
External Database Search STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr Detailed Information CELLULAR PROCESS Pyroptosis RNA TYPE miRNA ASSOCIATED CANCER TYPE Breast Cancer ADDITIONAL REFERENCE External Link ↗ RNA Name: hsa-miR-573 Mechanism of Action: Mediates high expression of GSDMC, linked to pyroptosis Effect on Cancer: Associated with worse prognosis and immune infiltration in breast cancer PMID: 36042287

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