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Cell Death Database

Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities

388 research entries found
RNA Name Mechanism of Action Effect on Cancer Reference
NBR2
lncRNA
Inhibits autophagy under starvation Suppresses proliferation and enhances survival rate PMID: 39349960

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Autophagy
lncRNA
Breast Cancer

RNA Name: NBR2

Mechanism of Action: Inhibits autophagy under starvation

Effect on Cancer: Suppresses proliferation and enhances survival rate

PMID: 39349960
DARS-AS1
lncRNA
Suppresses TGF-β/Smad3 signaling-induced autophagy Increases DOX sensitivity PMID: 37544559

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Autophagy
lncRNA
Breast Cancer

RNA Name: DARS-AS1

Mechanism of Action: Suppresses TGF-β/Smad3 signaling-induced autophagy

Effect on Cancer: Increases DOX sensitivity

PMID: 37544559
DANCR
lncRNA
Regulates miR-758-3p-PAX6 axis Promotes apoptosis and autophagy PMID: 32581581

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Autophagy
lncRNA
Breast Cancer

RNA Name: DANCR

Mechanism of Action: Regulates miR-758-3p-PAX6 axis

Effect on Cancer: Promotes apoptosis and autophagy

PMID: 32581581
OTUD6B-AS1
lncRNA
miR-26a-5p/MTDH pathway Promotes paclitaxel resistance PMID: 34740994

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Autophagy
lncRNA
Breast Cancer

RNA Name: OTUD6B-AS1

Mechanism of Action: miR-26a-5p/MTDH pathway

Effect on Cancer: Promotes paclitaxel resistance

PMID: 34740994
SNHG3
lncRNA
c-Myc/SNHG3/mTOR axis Promotes autophagy and inhibits migration PMID: 36963166

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Autophagy
lncRNA
Breast Cancer

RNA Name: SNHG3

Mechanism of Action: c-Myc/SNHG3/mTOR axis

Effect on Cancer: Promotes autophagy and inhibits migration

PMID: 36963166
PRKCQ-AS1
lncRNA
miR-361-5p/PIK3C3 mediated Regulates paclitaxel resistance PMID: 36732923

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Autophagy
lncRNA
Breast Cancer

RNA Name: PRKCQ-AS1

Mechanism of Action: miR-361-5p/PIK3C3 mediated

Effect on Cancer: Regulates paclitaxel resistance

PMID: 36732923
GAS5
lncRNA
overexpression of GAS5 led to an increase in ULK1/2 protein levels By promoting the activation of ULK1/2 and initiating autophagy PMID: 32705220

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Autophagy
lncRNA
Breast Cancer

RNA Name: GAS5

Mechanism of Action: overexpression of GAS5 led to an increase in ULK1/2 protein levels

Effect on Cancer: By promoting the activation of ULK1/2 and initiating autophagy

PMID: 32705220
HOTAIR
lncRNA
HOTAIR can act as a sponge for miRNA-34a HOTAIR promotes the invasion of breast cancer cells through β-catenin and MMPs PMID: 29469819

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Autophagy
lncRNA
Breast Cancer

RNA Name: HOTAIR

Mechanism of Action: HOTAIR can act as a sponge for miRNA-34a

Effect on Cancer: HOTAIR promotes the invasion of breast cancer cells through β-catenin and MMPs

PMID: 29469819
H19
lncRNA
Induces autophagy activation via the H19/SAHH/DNMT3B axis, Promotes tamoxifen resistance in breast cancer via autophagy PMID: 31340867

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Autophagy
lncRNA
Breast Cancer

RNA Name: H19

Mechanism of Action: Induces autophagy activation via the H19/SAHH/DNMT3B axis,

Effect on Cancer: Promotes tamoxifen resistance in breast cancer via autophagy

PMID: 31340867
EGOT
lncRNA
Upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions EGOT enhances autophagy, sensitizes cancer cells to paclitaxel PMID: 30999914

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Autophagy
lncRNA
Breast Cancer

RNA Name: EGOT

Mechanism of Action: Upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions

Effect on Cancer: EGOT enhances autophagy, sensitizes cancer cells to paclitaxel

PMID: 30999914