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Cell Death Database

Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities

388 research entries found
RNA Name Mechanism of Action Effect on Cancer Reference
miR-20a
miRNA
Targets RB1CC1/FIP200, negatively regulates autophagy Attenuates basal and rapamycin-induced autophagy PMID: 26829385

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-20a

Mechanism of Action: Targets RB1CC1/FIP200, negatively regulates autophagy

Effect on Cancer: Attenuates basal and rapamycin-induced autophagy

PMID: 26829385
miR-20b
miRNA
Targets RB1CC1/FIP200, negatively regulates autophagy Attenuates basal and rapamycin-induced autophagy PMID: 26829385

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-20b

Mechanism of Action: Targets RB1CC1/FIP200, negatively regulates autophagy

Effect on Cancer: Attenuates basal and rapamycin-induced autophagy

PMID: 26829385
miR-195
miRNA
Targets mitofusin-2, upregulates autophagy Enhances mitochondrial SOD-2 expression, promotes apoptosis PMID: 30932749

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-195

Mechanism of Action: Targets mitofusin-2, upregulates autophagy

Effect on Cancer: Enhances mitochondrial SOD-2 expression, promotes apoptosis

PMID: 30932749
miR-155
miRNA
Targets UBQLN1, upregulates autophagy Inhibits lipogenesis, promotes fat loss PMID: 37017334

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-155

Mechanism of Action: Targets UBQLN1, upregulates autophagy

Effect on Cancer: Inhibits lipogenesis, promotes fat loss

PMID: 37017334
miR-23b
miRNA
Downregulated by SFN, upregulates autophagy-related processes Promotes cell cycle arrest and senescence, induces autophagy PMID: 28912888

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-23b

Mechanism of Action: Downregulated by SFN, upregulates autophagy-related processes

Effect on Cancer: Promotes cell cycle arrest and senescence, induces autophagy

PMID: 28912888
miR-92b
miRNA
Downregulated by SFN, upregulates autophagy-related processes Promotes cell cycle arrest and senescence, induces autophagy PMID: 28912888

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Autophagy
miRNA
Breast Cancer

RNA Name: miR-92b

Mechanism of Action: Downregulated by SFN, upregulates autophagy-related processes

Effect on Cancer: Promotes cell cycle arrest and senescence, induces autophagy

PMID: 28912888
hsa-miR-148a-3p
miRNA
Identified as part of a necroptosis-related miRNA signature; predicts breast cancer prognosis. Poor prognosis; associated with cell death regulation and tumor progression. PMID: 35371342

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Necroptosis
miRNA
Breast Cancer

RNA Name: hsa-miR-148a-3p

Mechanism of Action: Identified as part of a necroptosis-related miRNA signature; predicts breast cancer prognosis.

Effect on Cancer: Poor prognosis; associated with cell death regulation and tumor progression.

PMID: 35371342
hsa-miR-223-3p
miRNA
Included in necroptosis-associated miRNA profiling; affects cell death pathways. Correlated with metastatic potential and tumor aggressiveness. PMID: 35371342

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Necroptosis
miRNA
Breast Cancer

RNA Name: hsa-miR-223-3p

Mechanism of Action: Included in necroptosis-associated miRNA profiling; affects cell death pathways.

Effect on Cancer: Correlated with metastatic potential and tumor aggressiveness.

PMID: 35371342
hsa-miR-331-3p
miRNA
Strongly associated with necroptosis and breast cancer prognosis. Poor prognosis; enriched in transcriptional regulation and membrane trafficking genes. PMID: 35371342

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Necroptosis
miRNA
Breast Cancer

RNA Name: hsa-miR-331-3p

Mechanism of Action: Strongly associated with necroptosis and breast cancer prognosis.

Effect on Cancer: Poor prognosis; enriched in transcriptional regulation and membrane trafficking genes.

PMID: 35371342
hsa-miR-181c-5p
miRNA
Targets BCL2 in LINC00665/miR-181c-5p/BCL2 axis for necroptosis regulation. Promotes necroptosis; linked to poor outcomes in breast cancer. PMID: 35251139

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Necroptosis
miRNA
Breast Cancer

RNA Name: hsa-miR-181c-5p

Mechanism of Action: Targets BCL2 in LINC00665/miR-181c-5p/BCL2 axis for necroptosis regulation.

Effect on Cancer: Promotes necroptosis; linked to poor outcomes in breast cancer.

PMID: 35251139