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Cell Death Database

Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities

388 research entries found
RNA Name Mechanism of Action Effect on Cancer Reference
circ_0001142
circRNA
circ_0001142/miR-361-3p/PIK3CB pathway Interferes with autophagy and macrophage polarization PMID: 35091089

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Autophagy
circRNA
Breast Cancer

RNA Name: circ_0001142

Mechanism of Action: circ_0001142/miR-361-3p/PIK3CB pathway

Effect on Cancer: Interferes with autophagy and macrophage polarization

PMID: 35091089
circ-DNMT1
circRNA
p53 and AUF1 interaction Enhances progression by activating autophagy PMID: 29973691

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Autophagy
circRNA
Breast Cancer

RNA Name: circ-DNMT1

Mechanism of Action: p53 and AUF1 interaction

Effect on Cancer: Enhances progression by activating autophagy

PMID: 29973691
circIQCH
circRNA
miR-139-5p/NFIB pathway Promotes autophagy and malignant progression PMID: 38884150

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Autophagy
circRNA
Breast Cancer

RNA Name: circIQCH

Mechanism of Action: miR-139-5p/NFIB pathway

Effect on Cancer: Promotes autophagy and malignant progression

PMID: 38884150
circ-DNMT1
circRNA
Regulating the oncogenic proteins P53 and AUF1 in breast cancer cells. Enhance the autophagy of breast cancer cells and promote breast cancer progression PMID: 29973691

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Autophagy
circRNA
Breast Cancer

RNA Name: circ-DNMT1

Mechanism of Action: Regulating the oncogenic proteins P53 and AUF1 in breast cancer cells.

Effect on Cancer: Enhance the autophagy of breast cancer cells and promote breast cancer progression

PMID: 29973691
circ0006528
circRNA
Promotes the expression of LC3-II Induce autophagy in breast cancer cells PMID: 33061434

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Autophagy
circRNA
Breast Cancer

RNA Name: circ0006528

Mechanism of Action: Promotes the expression of LC3-II

Effect on Cancer: Induce autophagy in breast cancer cells

PMID: 33061434
circABCB10
circRNA
circABCB10 adsorbs LET7A-5p to function as ceRNA, thereby promoting the expression of DUSP7 Promote autophagy in breast cancer cells and paclitaxel drug resistance PMID: 32273769

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Autophagy
circRNA
Breast Cancer

RNA Name: circABCB10

Mechanism of Action: circABCB10 adsorbs LET7A-5p to function as ceRNA, thereby promoting the expression of DUSP7

Effect on Cancer: Promote autophagy in breast cancer cells and paclitaxel drug resistance

PMID: 32273769
hsa_circ_0092276
circRNA
Altering autophagy-related gene 7 (ATG7) via sponging miR-384 Contribute to doxorubicin-resistance in Breast cancer cells PMID: 34023560

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Autophagy
circRNA
Breast Cancer

RNA Name: hsa_circ_0092276

Mechanism of Action: Altering autophagy-related gene 7 (ATG7) via sponging miR-384

Effect on Cancer: Contribute to doxorubicin-resistance in Breast cancer cells

PMID: 34023560
circSEPT9
circRNA
circSEPT9 sponge miR-637 mechanism involved remains unclear. PMID: 32264877

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Autophagy
circRNA
Breast Cancer

RNA Name: circSEPT9

Mechanism of Action: circSEPT9 sponge miR-637

Effect on Cancer: mechanism involved remains unclear.

PMID: 32264877
circSEPT9
circRNA
Inhibits ferroptosis by upregulating GCH1 via SRSF1 Reduces DDP chemosensitivity in TNBC PMID: 38040194

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Ferroptosis
circRNA
Breast Cancer

RNA Name: circSEPT9

Mechanism of Action: Inhibits ferroptosis by upregulating GCH1 via SRSF1

Effect on Cancer: Reduces DDP chemosensitivity in TNBC

PMID: 38040194
crVDAC3
circRNA
Impeding HSPB1 ubiquitination, reduces ferroptosis Confers T-DXd resistance in HER2-low BC PMID: 39243601

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Ferroptosis
circRNA
Breast Cancer

RNA Name: crVDAC3

Mechanism of Action: Impeding HSPB1 ubiquitination, reduces ferroptosis

Effect on Cancer: Confers T-DXd resistance in HER2-low BC

PMID: 39243601