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Cell Death Database

Comprehensive RNA involved in Cell Death Pathways research database with advanced search and filtering capabilities

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388 research entries found
RNA Name Mechanism of Action Effect on Cancer Reference
hsa-miR-146a-5p
miRNA 		Targets SOX5 (and TR6/IRAK1) to inhibit NF-κB/PI3K signaling hsa-miR-146a-5p was downregulated in BC is a tumor suppressor miRNA PMID: 38250762

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-146a-5p

Mechanism of Action: Targets SOX5 (and TR6/IRAK1) to inhibit NF-κB/PI3K signaling

Effect on Cancer: hsa-miR-146a-5p was downregulated in BC is a tumor suppressor miRNA

PMID: 38250762
hsa-miR-191-5p
miRNA 		Targets SOX4 (and p53 loop regulators) to repress apoptosis Oncogenic; inhibits apoptosis and promotes proliferation/chemoresistance PMID: 28450532

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-191-5p

Mechanism of Action: Targets SOX4 (and p53 loop regulators) to repress apoptosis

Effect on Cancer: Oncogenic; inhibits apoptosis and promotes proliferation/chemoresistance

PMID: 28450532
hsa-miR-199a-3p
miRNA 		miR-199a can induce apoptosis either by up-regulating the level of pro-apoptotic protein or decreasing the expression of anti-apoptotic protein Inhibits cell proliferation and cycle progression/Reduces the risk of breast cancer PMID: 26399456

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-199a-3p

Mechanism of Action: miR-199a can induce apoptosis either by up-regulating the level of pro-apoptotic protein or decreasing the expression of anti-apoptotic protein

Effect on Cancer: Inhibits cell proliferation and cycle progression/Reduces the risk of breast cancer

PMID: 26399456
hsa-miR-199a-5p
miRNA 		miR-199a can induce apoptosis either by up-regulating the level of pro-apoptotic protein or decreasing the expression of anti-apoptotic protein Inhibits cell proliferation and cycle progression/Reduces the risk of breast cancer PMID: 27094578

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-199a-5p

Mechanism of Action: miR-199a can induce apoptosis either by up-regulating the level of pro-apoptotic protein or decreasing the expression of anti-apoptotic protein

Effect on Cancer: Inhibits cell proliferation and cycle progression/Reduces the risk of breast cancer

PMID: 27094578
hsa-miR-199b-5p
miRNA 		Targets DDR1 (DDR tyrosine kinase) and promotes apoptosis Downregulation is correlated with aggressive clinical characteristics of breast cancer PMID: 36980974

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-199b-5p

Mechanism of Action: Targets DDR1 (DDR tyrosine kinase) and promotes apoptosis

Effect on Cancer: Downregulation is correlated with aggressive clinical characteristics of breast cancer

PMID: 36980974
hsa-miR-224-5p
miRNA 		Targets HOXA9 (homeobox) and promoted apoptosis Oncogenic; promotes proliferation and inhibits apoptosis (knockdown induces apoptosis) PMID: 33869743

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-224-5p

Mechanism of Action: Targets HOXA9 (homeobox) and promoted apoptosis

Effect on Cancer: Oncogenic; promotes proliferation and inhibits apoptosis (knockdown induces apoptosis)

PMID: 33869743
hsa-miR-24-3p
miRNA 		Targets CDKN1B (p27Kip1) and inhibits apoptosis Oncogenic; promotes proliferation and confers drug resistance (inhibits apoptosis) PMID: 26044523

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-24-3p

Mechanism of Action: Targets CDKN1B (p27Kip1) and inhibits apoptosis

Effect on Cancer: Oncogenic; promotes proliferation and confers drug resistance (inhibits apoptosis)

PMID: 26044523
hsa-miR-302d-3p
miRNA 		Targets TMBIM6 and promotes apoptosis Tumor suppressor; inhibits proliferation and migration, induces apoptosis PMID: 34651659

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-302d-3p

Mechanism of Action: Targets TMBIM6 and promotes apoptosis

Effect on Cancer: Tumor suppressor; inhibits proliferation and migration, induces apoptosis

PMID: 34651659
hsa-miR-30a-3p
miRNA 		Targets cell-cycle genes (e.g. ANLN) and induces apoptosis Tumor suppressor; inhibits proliferation and metastasis PMID: 39728605

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-30a-3p

Mechanism of Action: Targets cell-cycle genes (e.g. ANLN) and induces apoptosis

Effect on Cancer: Tumor suppressor; inhibits proliferation and metastasis

PMID: 39728605
hsa-miR-31-5p
miRNA 		Overexpression of miR?31?5p inhibited cell proliferation and promoted apoptosis Tumor suppressor; can enhance chemotherapy response (Taxol) PMID: 31853314

External Database Search

STRING-DB miRTarDB PDB Encori TargetScan SM2miR DLnc OncoLnc Enrichr

Detailed Information

Apoptosis
miRNA
Breast Cancer
RNA Name: hsa-miR-31-5p

Mechanism of Action: Overexpression of miR?31?5p inhibited cell proliferation and promoted apoptosis

Effect on Cancer: Tumor suppressor; can enhance chemotherapy response (Taxol)

PMID: 31853314